Extending the time window for Tenecteplase by Effective RecanalizatioN of bAsilar artery occLusion in patients with POSTerior circulation stroke
Lead PI: Dr Fana Alemseged
Participating Australian and New Zealand Sites: TBC
Status: Site selection, governance submission. Recruitment to commence within 3 months.
No. of Patients Currently Recruited: No. of Patients Required:
Primary Objective: to test the hypothesis that the thrombolytic tenecteplase (TNK, 0.25mg/kg) ± thrombectomy administered within 24 hours after symptoms onset, is superior to current best practice (alteplase, rtPA, 0.9mg/kg or standard care/no lysis ± thrombectomy) in achieving excellent functional outcome (mRS 0-1) or return to the premorbid modified Rankin Scale at 90 days in patients with acute ischaemic stroke due to basilar artery occlusion.