Current Trials

Below are a list of trials currently endorsed by the ASTN. You can click on the trial tags to help streamline your search

ASPIRING logo
ASPIRING

Antiplatelet Secondary Prevention International Randomised trial after INtracerebral haemorrhaGe Lead PI: Professor Graeme J. Hankey and Professor Craig S. Anderson  Participating Australian and New…

ATTUNE

ATrial fibrillation in sTroke; Utility of Neuroimaging Evaluation Lead PI: Prof Mark Parsons Status: Recruiting No. of Patients Currently Recruited: 256                                No. of Patients…

avert dose logo revised
AVERT DOSE

A trial to Determine the Optimal early mobility Training after Stroke AVERT DOSE: A trial to Determine the Optimal early…

Screen Shot 2022-05-18 at 3.14.34 pm
CASPER

CASPER: Colchicine After Stroke to Prevent Event Recurrence Chief Investigator A: Prof. Anthony Keech, NHMRC Clinical Trial Centre Chief Investigator…

CHARM

Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentre, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe…

DIRECT-SAFE
DIRECT-SAFE

A randomised controlled trial of DIRECT endovascular clot retrieval versus standard bridging thrombolysis with endovascular clot retrieval within 4.5 hours…

ESCAPE-Next
ESCAPE-Next

A Multicentre, Randomized, Double-blinded, Placebo-controlled, Parallel Group, Single-dose Design to Determine the Efficacy and Safety of Nerinetide in Participants with…

EVACUATE
EVACUATE-RCT

Ultra-Early, Minimally inVAsive intraCerebral Haemorrhage evacUATion Versus Standard trEatment Lead PI: Prof Timothy Kleinig Status: ASTN endorsed, Site selection, Recruiting…

EVIP

Early Vocational Intervention of People after Stroke: A Randomised Pilot Trial Lead PI: Prof Natasha Lannin Status: Recruiting No. of Patients Currently…

INTERACT3
INTERACT3

INTEnsive care bundle with blood pressure Reduction in Acute Cerebral haemorrhage Trial Lead PI:  Prof. Craig Anderson Status: Recruiting No. of…

MAEStro

A Randomized, Double-Blind, Placebo-Controlled,Dose-Response Efficacy and Safety Study of MLC1501 in Patients with Stroke   Lead PI: A/Prof Christopher CHEN…

MASTERS-2
MASTERS-2

MultiStem Administration for Stroke Treatment and Enhanced Recovery Study Lead PI: N/A Status: Site Selection No. of Patients Currently Recruited: 0                               No. of Patients…

MIDAS 2

Modafinil In Debilitating Fatigue After Stroke 2 Lead PI: Prof Chris Levi and Dr Andrew Bivard Status:  Recruiting  No. of…

OPTIMISTmain
OPTIMISTmain

Optimal Post rTpa-Iv Monitoring in Ischemic Stroke Lead PI: Professor Craig Anderson Status: Recruiting, Site selection No. of Patients Currently Recruited: 18 …

Pacific-Stroke
Pacific-Stroke

Phase 2 Program of AntiCoagulation via Inhibition of FXIa by the oral Compound BAY 2433334 – non-cardioembolic STROKE study (PACIFIC-STROKE)…

PESTO

 A Prospective multicentre, phase 2b randomised controlled double-blind trial, to determine the safety and efficacy of perispinal etanercept on quality…

POST-ETERNAL Logo
POST-ETERNAL

Extending the time window for Tenecteplase by Effective RecanalizatioN of bAsilar artery occLusion in patients with POSTerior circulation stroke Lead PI:  Dr Fana Alemseged Participating…

RECAPS
ReCAPS

Recovery-focused Community support to Avoid readmissions and improve Participation after Stroke ReCAPS: Recovery-focused Community support to Avoid readmissions and improve Participation…

Screen Shot 2022-05-18 at 3.42.17 pm
STARS

Safety and Tolerability of AZD6482 in Reperfusion for Stroke (STARS) Study Lead PI: Dr Candice Delcourt Status: Recruiting No. of…

STOP-MSU

Stopping haemorrhage with Tranexamic acid for hyperacute Onset Presentation including Mobile Stroke Units Lead PI: Prof Stephen Davis, Prof Geoff Donnan,…

TACTICS
TACTICS

Trial of Advance CT Imaging and Combined Education Support for stroke patient access to endovascular therapy (EVT) using a hub…

TASTE
TASTE

Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation (TASTE) Trial Lead PI: Professor Mark Parsons Status: Recruiting No. of Patients Currently Recruited: 453  …