Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation (TASTE) Trial

Lead PI: Professor Mark Parsons

Status: Recruiting

No. of Patients Currently Recruited: 453                                No. of Patients Required: 728

Multicentre, prospective, randomised open-label blinded endpoint (PROBE) phase III study including acute stroke patients with hemispheric ischaemia who have penumbra on perfusion CT (CTP) or MRI within 4.5 hours of stroke onset. The primary objective of this study is to test the hypothesis that patients with acute hemispheric ischaemic stroke who have a penumbra on perfusion CT or MRI within 4.5hrs of symptom onset will have less disability at 3 months when treated with IV TNK compared to IV tPA.

Trial URL:



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